PLOS Thesaurus

Last uploaded: September 21, 2017

Id	http://localhost/plosthes.2017-1#11255 http://localhost/plosthes.2017-1#11255
Preferred Name	Antiviral immune response
Type	http://www.w3.org/2004/02/skos/core#Concept

prefLabel	Antiviral immune response
homepage	http://journals.plos.org/plosone/browse/antiviral_immune_response
type	http://www.w3.org/2004/02/skos/core#Concept http://www.w3.org/2002/07/owl#NamedIndividual
Previous_Classification	10.210.100.20^Antiviral immune response\|60.180.100.20^Antiviral immune response
alpha	Antiviral immune response
scopeNote	Antiviral immunity Innate immune responses are the front line of defence of the host against virus infection. The host cell can detect an invading virus and induce expression of interferons (IFNs) and cytokines. In turn, these IFNs can establish an antiviral state in uninfected neighbouring cells by suppressing protein production, promoting the degradation of mRNA, and by inducing expression of a variety of IFN-stimulated gene products (ISGs) with broad antiviral activity. IFNs can also modulate the acquired immune response, activating immune effector cells and thereby providing a link between innate and adaptive immunity. http://www.gla.ac.uk/researchinstitutes/iii/cvr/researchprogrammes/antiviralimmunity/ RD
broader	http://localhost/plosthes.2017-1#7861
status	Accepted

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