Protein-ligand interaction ontology

Last uploaded: November 3, 2014
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Preferred Name

Hydrophobic_interaction
Synonyms
ID

http://www.semanticweb.org/ontologies/2010/3/Ontology1271664172453.owl#Hydrophobic_interaction
isDefinedBy

A favourable interaction between nonpolar substructures or surfaces in aqueous solution that is characterized by a large change in heat capacity. An interaction between a hydrophobic ('water-hating') part of a molecule and an aqueous environment. Particularly significant in establishing the conformation of molecules in solution, and thus their biological activity. Many enzymes have a structure where the polypeptide chain is folded to form a hydrophobic core and a hydrophilic ('water-loving') surface.
prefixIRI

Ontology1271664172453:Hydrophobic_interaction
prefLabel

Hydrophobic_interaction
Reference

http://www.nature.com/nrd/journal/v1/n4/glossary/nrd769_glossary.html http://www.bioportal.gc.ca/English/View.asp?x=696&mid=417
Synonym

hydrophobic interaction hydrophobic interactions hydrophobic forces hydrophobic force
subClassOf

http://www.semanticweb.org/ontologies/2010/3/Ontology1271664172453.owl#Non_bonded_interaction
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