Pre-eclampsia Ontology

Last uploaded: July 1, 2016
Preferred Name

Trophoblasts
Synonyms
ID

http://www.pepathway.org/peo/1.2#Trophoblasts

Definitions

Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA). Trophoblasts with multinuclear cytoplasm and undefined cellular structures. Syncytiotrophoblasts secrete proteolytic enzymes that erode the ENDOMETRIUM for EMBRYO IMPLANTATION. They also produce steroid, peptide, and protein hormones (PLACENTAL HORMONES). Trophoblasts with single nucleus and defined cellular structures. As the PLACENTA develops, pockets of cytotrophoblasts serve as stem cells for syncytiotrophoblasts.

label

Trophoblasts

mapping

http://purl.bioontology.org/ontology/MESH/D014327

prefixIRI

peo2:Trophoblasts

prefLabel

Trophoblasts

Synonym

Trophoblast

Cytotrophoblasts

Cytotrophoblast

Syncytiotrophoblast

Syncytiotrophoblasts

subClassOf

http://scai.fraunhofer.de/NDDUO#Cellular_and_subcellular_entities

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