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The Prescription of Drugs Ontology
Last uploaded:
September 4, 2020
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| Id | http://purl.obolibrary.org/obo/CHEBI_4305
http://purl.obolibrary.org/obo/CHEBI_4305
|
|---|---|
| Preferred Name | Dacarbazine |
| Definitions |
A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.
|
| Synonyms |
Dtic-Dome (TN)
4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
5-(3,3-dimethyltriazeno)imidazole-4-carboxamide
4-(dimethyltriazeno)imidazole-5-carboxamide
5-(dimethyltriazeno)imidazole-4-carboxamide
dacarbazina
dacarbazine
5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide
Di-me-triazenoimidazolecarboxamide
dacarbazinum
4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
DIC
DTIC
HSDB 3219
ICDMT
NCI-C04717
NSC 45388
NSC-45388
deticene
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
dacarbazine
Dacarbazine
|
|---|---|
| prefLabel |
Dacarbazine
|
| database_cross_reference |
PMID:12195827
PMID:21471822
LINCS:LSM-5487
Beilstein:521487
PMID:28250333
PMID:23318786
PMID:28419676
HMDB:HMDB0014989
DrugBank:DB00851
PMID:28096700
KEGG:D00288
Reaxys:521487
PMID:23029050
PMID:29076951
PMID:11318431
PMID:20082117
PMID:15010317
Wikipedia:Dacarbazine
PMID:29287706
KEGG:C06936
PMID:29305638
PMID:29296081
PMID:21654834
PMID:29344241
CAS:4342-03-4
PMID:28387914
PMID:29184162
PMID:26940170
PMID:10751609
Drug_Central:773
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|
| notation |
CHEBI:4305
|
| in_subset | |
| inchi |
InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)
|
| has_related_synonym |
Dtic-Dome (TN)
4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
5-(3,3-dimethyltriazeno)imidazole-4-carboxamide
4-(dimethyltriazeno)imidazole-5-carboxamide
5-(dimethyltriazeno)imidazole-4-carboxamide
dacarbazina
dacarbazine
5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide
Di-me-triazenoimidazolecarboxamide
dacarbazinum
4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
DIC
DTIC
HSDB 3219
ICDMT
NCI-C04717
NSC 45388
NSC-45388
deticene
See more
See less
|
| id |
CHEBI:4305
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| prefixIRI |
CHEBI:4305
|
| textual definition |
A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.
|
| formula |
C6H10N6O
|
| subClassOf | |
| inchikey |
FDKXTQMXEQVLRF-UHFFFAOYSA-N
|
| mass |
182.183
|
| monoisotopicmass |
182.09161
|
| type | |
| smiles |
C=1NC(=C(N1)C(=O)N)N=NN(C)C
|
| has_RxCUI |
3098
|
| has role | |
| has_exact_synonym |
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
|
| bearer_of | |
| alternative term |
Dtic-Dome (TN)
4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
5-(3,3-dimethyltriazeno)imidazole-4-carboxamide
4-(dimethyltriazeno)imidazole-5-carboxamide
5-(dimethyltriazeno)imidazole-4-carboxamide
dacarbazina
dacarbazine
5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide
Di-me-triazenoimidazolecarboxamide
dacarbazinum
4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
DIC
DTIC
HSDB 3219
ICDMT
NCI-C04717
NSC 45388
NSC-45388
deticene
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
See more
See less
|
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