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The Prescription of Drugs Ontology
Last uploaded:
September 4, 2020
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| Id | http://purl.obolibrary.org/obo/CHEBI_27899
http://purl.obolibrary.org/obo/CHEBI_27899
|
|---|---|
| Preferred Name | Cisplatin |
| Definitions |
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
|
| Synonyms |
[PtCl2(NH3)2]
Peyrone's salt
cisplatinum
Lederplatin
cis-diammineplatinum(II) dichloride
cis-Diamminedichloroplatinum(II)
cis-diamminedichloroplatinum
cis-dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
Peyrone's chloride
Briplatin
CDDP
Cismaplat
Neoplatin
Platamine
Platinex
Platinol
Randa
cis-DDP
cis-platin
cisplatin
cisplatine
cisplatino
(SP-4-2)-diamminedichloridoplatinum
cis-diamminedichloroplatinum(II)
cis-diamminedichloridoplatinum(II)
(SP-4-2)-diamminedichloroplatinum
Cisplatin
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Cisplatin
cisplatin
|
|---|---|
| prefLabel |
Cisplatin
|
| database_cross_reference |
DrugBank:DB00515
Wikipedia:Cisplatin
PMID:18472761
KEGG:D00275
PMID:23604226
PMID:12537968
Gmelin:2519
PMID:23651576
PMID:28494534
PMID:12831510
Reaxys:11324567
MetaCyc:CPD0-1392
PMID:1855275
PMID:16327988
Patent:DE2318020
PMID:12935404
KEGG:C06911
PMID:23554447
CAS:15663-27-1
Patent:DE2329485
HMDB:HMDB0014656
PMID:10883661
MolBase:25
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|
| notation |
CHEBI:27899
|
| in_subset | |
| inchi |
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
|
| has_related_synonym |
[PtCl2(NH3)2]
Peyrone's salt
cisplatinum
Lederplatin
cis-diammineplatinum(II) dichloride
cis-Diamminedichloroplatinum(II)
cis-diamminedichloroplatinum
cis-dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
Peyrone's chloride
Briplatin
CDDP
Cismaplat
Neoplatin
Platamine
Platinex
Platinol
Randa
cis-DDP
cis-platin
cisplatin
cisplatine
cisplatino
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|
| id |
CHEBI:27899
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| prefixIRI |
CHEBI:27899
|
| textual definition |
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
|
| formula |
Cl2H6N2Pt
H6Cl2N2Pt
|
| subClassOf | |
| inchikey |
LXZZYRPGZAFOLE-UHFFFAOYSA-L
|
| mass |
300.04452
|
| monoisotopicmass |
298.95560
|
| has_alternative_id |
CHEBI:23314
CHEBI:3722
|
| type | |
| smiles |
[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H]
|
| has_RxCUI |
2555
|
| has role |
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|
| has_exact_synonym |
(SP-4-2)-diamminedichloridoplatinum
cis-diamminedichloroplatinum(II)
cis-diamminedichloridoplatinum(II)
(SP-4-2)-diamminedichloroplatinum
Cisplatin
|
| bearer_of |
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|
| alternative term |
[PtCl2(NH3)2]
Peyrone's salt
cisplatinum
Lederplatin
cis-diammineplatinum(II) dichloride
cis-Diamminedichloroplatinum(II)
cis-diamminedichloroplatinum
cis-dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
Peyrone's chloride
Briplatin
CDDP
Cismaplat
Neoplatin
Platamine
Platinex
Platinol
Randa
cis-DDP
cis-platin
cisplatin
cisplatine
cisplatino
(SP-4-2)-diamminedichloridoplatinum
cis-diamminedichloroplatinum(II)
cis-diamminedichloridoplatinum(II)
(SP-4-2)-diamminedichloroplatinum
Cisplatin
See more
See less
|
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