Preferred Name |
mesalamine |
|
Synonyms |
Pentasa |
|
Definitions |
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000732182 |
|
altLabel |
Pentasa mesalazine Lialda 5-ASA Apriso 5-amino-2-hydroxybenzoic acid Rowasa Asacol 5-aminosalicylic acid |
|
CAS Registry |
89-57-6 |
|
cui |
C1873792 C0678172 C0678171 C0127615 C0699623 C2586541 |
|
DATE FIRST PUBLISHED |
2012-04-17 |
|
Date last modified |
2012-04-17 |
|
definition |
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. |
|
LT |
TRD |
|
notation |
CDR0000732182 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
mesalamine |
|
tui |
T109 T116 T121 |