Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

resveratrol

Synonyms

(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol

Definitions

A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1215" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1215" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000405819

altLabel

(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol

3,4',5-stilbenetriol

cui

C0073096

DATE FIRST PUBLISHED

2004-11-22

Date last modified

2008-10-13

definition

A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1215" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1215" NCI Thesaurus)

NCI ID

C1215

notation

CDR0000405819

ORIG STY

Drug/agent

prefLabel

resveratrol

tui

T109

T121

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http://purl.bioontology.org/ontology/MSHFRE/D000077185 MSHFRE CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179228 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/96383001 SNOMEDCT CUI
http://purl.bioontology.org/ontology/VANDF/4026034 VANDF CUI
http://purl.bioontology.org/ontology/SNMI/C-A6595 SNMI CUI
http://purl.bioontology.org/ontology/RXNORM/1000492 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D000077185 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000176093 NDFRT CUI
http://purl.bioontology.org/ontology/NDDF/013210 NDDF CUI
http://purl.bioontology.org/ontology/SCTSPA/96383001 SCTSPA CUI
http://purl.obolibrary.org/obo/XCO_0000856 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 CDNO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 FOODON LOOM
https://go.drugbank.com/drugs/DB02709 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96383001 SNOMEDCT LOOM
http://www.pepathway.org/peo/1.2#Resveratrol PE-O LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0073096 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4026034 VANDF LOOM
http://purl.jp/bio/4/id/200906085193911422 IOBC LOOM
http://purl.obolibrary.org/obo/dinto_DB02709 DINTO LOOM
http://purl.obolibrary.org/obo/ARO_3007614 ARO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1215 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-A6595 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/1000492 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D000077185 MESH LOOM
http://stirdf.jst.go.jp/id/200907035397714703 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176093 NDFRT LOOM
http://doe-generated-ontology.com/OntoAD#C0073096 ONTOAD LOOM
http://purl.obolibrary.org/obo/NCIT_C1215 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C059514 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/013210 NDDF LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 FOBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 GO-PLUS LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14749 OCHV LOOM