loading...| Preferred Name |
dextromethorphan hydrobromide |
|
| Synonyms |
DXM |
|
| Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042490 |
|
| altLabel |
DXM |
|
| Component of | ||
| cui |
C0350422 |
|
| Date last modified |
2010-06-01 |
|
| definition |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus) |
|
| Legacy PDQ ID |
6022 |
|
| NCI ID |
C423 |
|
| notation |
CDR0000042490 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
dextromethorphan hydrobromide |
|
| tui |
T109 T121 |