Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

dextromethorphan hydrobromide

Synonyms

DXM

Definitions

The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000042490

altLabel

DXM

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000043324

cui

C0350422

Date last modified

2010-06-01

definition

The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus)

Legacy PDQ ID

6022

NCI ID

C423

notation

CDR0000042490

ORIG STY

Drug/agent

prefLabel

dextromethorphan hydrobromide

tui

T109

T121

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http://stirdf.jst.go.jp/id/200907066744749850 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4018051 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4018051 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/102490 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/102490 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/001653 NDDF CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423 NCIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000179490 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D003915 MESH CUI
http://sbmi.uth.tmc.edu/ontology/ochv#C0350422 OCHV LOOM
http://www.co-ode.org/ontologies/galen#DextromethorphanHydrobromide GALEN LOOM
http://purl.bioontology.org/ontology/SCTSPA/387237004 SCTSPA CUI
http://purl.jp/bio/4/id/200906067684261731 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146392 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146392 NDFRT LOOM
http://purl.bioontology.org/ontology/RCD/cg2.. RCD CUI
http://purl.bioontology.org/ontology/RCD/cg2.. RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387237004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387237004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-88131 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-88131 SNMI LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005736 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005736 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005736 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005741 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005741 DMTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4471 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4471 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4471 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#31301 OCHV LOOM
http://purl.bioontology.org/ontology/MSHFRE/D003915 MSHFRE CUI