idarubicin hydrochloride

idarubicin HCl

The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1587" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1587" NCI Thesaurus)

http://purl.bioontology.org/ontology/PDQ/CDR0000039753

idarubicin HCl

4-demethoxydaunomycin

SC-33428

DMDR

Zavedos

4DMDR

4-demethoxydaunorubicin

Idamycin PFS

IDA

4-DMDR

IMI-30

57852-57-0

http://purl.bioontology.org/ontology/PDQ/CDR0000042061

http://purl.bioontology.org/ontology/PDQ/CDR0000042520

http://purl.bioontology.org/ontology/PDQ/CDR0000424451

http://purl.bioontology.org/ontology/PDQ/CDR0000038582

http://purl.bioontology.org/ontology/PDQ/CDR0000039631

http://purl.bioontology.org/ontology/PDQ/CDR0000258376

http://purl.bioontology.org/ontology/PDQ/CDR0000041238

http://purl.bioontology.org/ontology/PDQ/CDR0000042910

http://purl.bioontology.org/ontology/PDQ/CDR0000041471

http://purl.bioontology.org/ontology/PDQ/CDR0000269068

http://purl.bioontology.org/ontology/PDQ/CDR0000043263

http://purl.bioontology.org/ontology/PDQ/CDR0000038427

http://purl.bioontology.org/ontology/PDQ/CDR0000041582

http://purl.bioontology.org/ontology/PDQ/CDR0000042040

http://purl.bioontology.org/ontology/PDQ/CDR0000042002

http://purl.bioontology.org/ontology/PDQ/CDR0000353152

http://purl.bioontology.org/ontology/PDQ/CDR0000042590

http://purl.bioontology.org/ontology/PDQ/CDR0000043240

http://purl.bioontology.org/ontology/PDQ/CDR0000038067

http://purl.bioontology.org/ontology/PDQ/CDR0000041737

http://purl.bioontology.org/ontology/PDQ/CDR0000390236

http://purl.bioontology.org/ontology/PDQ/CDR0000039766

http://purl.bioontology.org/ontology/PDQ/CDR0000043246

http://purl.bioontology.org/ontology/PDQ/CDR0000041470

http://purl.bioontology.org/ontology/PDQ/CDR0000042202

http://purl.bioontology.org/ontology/PDQ/CDR0000042172

http://purl.bioontology.org/ontology/PDQ/CDR0000039629

http://purl.bioontology.org/ontology/PDQ/CDR0000258412

http://purl.bioontology.org/ontology/PDQ/CDR0000354250

http://purl.bioontology.org/ontology/PDQ/CDR0000038888

http://purl.bioontology.org/ontology/PDQ/CDR0000042031

http://purl.bioontology.org/ontology/PDQ/CDR0000042041

http://purl.bioontology.org/ontology/PDQ/CDR0000041754

http://purl.bioontology.org/ontology/PDQ/CDR0000042122

http://purl.bioontology.org/ontology/PDQ/CDR0000042123

http://purl.bioontology.org/ontology/PDQ/CDR0000041720

http://purl.bioontology.org/ontology/PDQ/CDR0000353151

http://purl.bioontology.org/ontology/PDQ/CDR0000041721

http://purl.bioontology.org/ontology/PDQ/CDR0000042127

http://purl.bioontology.org/ontology/PDQ/CDR0000043239

http://purl.bioontology.org/ontology/PDQ/CDR0000043033

http://purl.bioontology.org/ontology/PDQ/CDR0000041128

http://purl.bioontology.org/ontology/PDQ/CDR0000042333

http://purl.bioontology.org/ontology/PDQ/CDR0000042393

http://purl.bioontology.org/ontology/PDQ/CDR0000042342

http://purl.bioontology.org/ontology/PDQ/CDR0000041581

http://purl.bioontology.org/ontology/PDQ/CDR0000350368

http://purl.bioontology.org/ontology/PDQ/CDR0000042174

http://purl.bioontology.org/ontology/PDQ/CDR0000041129

http://purl.bioontology.org/ontology/PDQ/CDR0000393558

C0939353

C0284597

C0086450

C0282388

C0592279

C0020789

2018-05-17

The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1587" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1587" NCI Thesaurus)

2414

TRD

C1587

CDR0000039753

Drug/agent

idarubicin hydrochloride

T109

T195

T121