Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

recombinant oxytocin

Synonyms

oxytocin

Definitions

A synthetic cyclic peptide form of the naturally occurring posterior pituitary hormone oxytocin. Oxytocin binds to oxytocin receptors in the uterine myometrium, which triggers the G-protein coupled receptor signal transduction cascade that causes increased intracellular calcium concentrations. Increased calcium concentration levels activate myosin light chain kinase which, in turn, induces the formation of the contractile protein actomyosin. This stimulates uterine smooth muscle contractions. This agent also stimulates smooth muscles in the mammary glands, thereby causing lactation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C724" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C724" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039293

altLabel

oxytocin

Pitocin

Syntocinon

CAS Registry

50-56-6

cui

C0733348

C1704206

C0592155

C0030095

Date last modified

2015-09-15

definition

A synthetic cyclic peptide form of the naturally occurring posterior pituitary hormone oxytocin. Oxytocin binds to oxytocin receptors in the uterine myometrium, which triggers the G-protein coupled receptor signal transduction cascade that causes increased intracellular calcium concentrations. Increased calcium concentration levels activate myosin light chain kinase which, in turn, induces the formation of the contractile protein actomyosin. This stimulates uterine smooth muscle contractions. This agent also stimulates smooth muscles in the mammary glands, thereby causing lactation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C724" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C724" NCI Thesaurus)

Legacy PDQ ID

1926

LT

TRD

NCI ID

C724

notation

CDR0000039293

ORIG STY

Drug/agent

prefLabel

recombinant oxytocin

tui

T125

T116

T121

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/SCTSPA/12369008 SCTSPA CUI
http://purl.bioontology.org/ontology/RCD/x02s3 RCD CUI
http://purl.bioontology.org/ontology/VANDF/4018039 VANDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006473 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D010121 MESH CUI
http://purl.bioontology.org/ontology/MESH/D010121 MESH CUI
http://purl.bioontology.org/ontology/MESH/D010121 MESH CUI
http://purl.bioontology.org/ontology/SNMI/F-B1820 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/112115002 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/12369008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/RCD/X80G9 RCD CUI
http://purl.bioontology.org/ontology/SNMI/C-A0D05 SNMI CUI
http://purl.bioontology.org/ontology/RCD/g15.. RCD CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C724 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C724 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/001307 NDDF CUI
http://purl.bioontology.org/ontology/LNC/LP15767-4 LOINC CUI
http://purl.bioontology.org/ontology/SCTSPA/112115002 SCTSPA CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146381 NDFRT CUI
http://purl.bioontology.org/ontology/LNC/MTHU013002 LOINC CUI
http://purl.bioontology.org/ontology/MSHFRE/D010121 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D010121 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D010121 MSHFRE CUI
http://purl.bioontology.org/ontology/RXNORM/7824 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/227199 RXNORM CUI
http://purl.bioontology.org/ontology/CSP/2334-5056 CRISP CUI
http://purl.bioontology.org/ontology/UATC/H01BB02 ATC CUI