loading...| Preferred Name |
therapeutic estradiol |
|
| Synonyms |
(17beta)-estra-1,3,5(10)-triene-3,17-diol |
|
| Definitions |
A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C478" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C478" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039236 |
|
| altLabel |
(17beta)-estra-1,3,5(10)-triene-3,17-diol Estrace Estraldine Ovocylin Diogynets Aquadiol Diogyn Dimenformon Vagifem Vivelle 17 beta-estradiol ESDL Progynon |
|
| CAS Registry |
50-28-2 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000041316 http://purl.bioontology.org/ontology/PDQ/CDR0000357621 |
|
| cui |
C0878474 C0699359 C0699352 C0724374 C0878476 C0878472 C0878477 C0878475 C0014912 C0592238 |
|
| Date last modified |
2015-09-25 |
|
| definition |
A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C478" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C478" NCI Thesaurus) |
|
| Legacy PDQ ID |
1858 |
|
| LT |
TRD |
|
| NCI ID |
C478 |
|
| notation |
CDR0000039236 |
|
| NSC Code |
9895 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
therapeutic estradiol |
|
| tui |
T125 T109 T121 |