Preferred Name |
therapeutic progesterone |
|
Synonyms |
progesterone |
|
Definitions |
A synthetic form of the endogenous hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C777" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C777" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039059 |
|
altLabel |
progesterone Prolidon delta4-pregnene-3,20-dione Cyclogest Progestin Progesterol Lutocylin Gestiron Progestogel PRG Utrogestan Luteohormone Lucorteum Sol Colprosterone Lutogyl Lutocyclin Gestone Gesterol 100 Progestasert Syngesterone Lutromone Progestol Progeston Corluvite Prolutin Lutocylin M Lipo-Lutin Corlutina |
|
CAS Registry |
57-83-0 |
|
Component of | ||
cui |
C1515394 C1515397 C1515395 C1515396 C0591309 C1515400 C1515392 C0701115 C1515391 C0591564 C1515399 C1515388 C4732944 C0701111 C0033306 C1515389 C1515398 C1515393 C0033308 C0701113 C0701119 C0701120 C0701116 C0701118 C4732945 C1515390 |
|
Date last modified |
2008-10-22 |
|
definition |
A synthetic form of the endogenous hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C777" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C777" NCI Thesaurus) |
|
Legacy PDQ ID |
1643 |
|
LT |
TRD |
|
NCI ID |
C777 |
|
notation |
CDR0000039059 |
|
NSC Code |
9704 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
therapeutic progesterone |
|
tui |
T125 T109 T121 |