Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

aminolevulinic acid
Synonyms

d-amino-levulinic acid

delta aminolevulinic acid

5-aminolevulinic acid

5-amino-4-oxopentanoic acid

amino-levulinic acid

5-ALA

5-aminolaevulinic acid

delta-aminolevulinic acid
Definitions

A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C234" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C234" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000791850
altLabel

d-amino-levulinic acid

delta aminolevulinic acid

5-aminolevulinic acid

5-amino-4-oxopentanoic acid

amino-levulinic acid

5-ALA

5-aminolaevulinic acid

delta-aminolevulinic acid
CAS Registry

106-60-5
cui

C0002563
DATE FIRST PUBLISHED

2018-01-08
Date last modified

2018-01-08
definition

A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C234" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C234" NCI Thesaurus)
NCI ID

C234
notation

CDR0000791850
ORIG STY

Drug/agent
prefLabel

aminolevulinic acid
tui

T116

T123

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/NDFRT/N0000170216 NDFRT CUI
http://purl.bioontology.org/ontology/SNMI/F-64810 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/409398000 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/259496005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/MESH/D000622 MESH CUI
http://purl.bioontology.org/ontology/RCD/X80L1 RCD CUI
http://purl.bioontology.org/ontology/RXNORM/683 RXNORM CUI
http://purl.bioontology.org/ontology/SCTSPA/259496005 SCTSPA CUI
http://purl.bioontology.org/ontology/ATC/L01XD04 ATC CUI
http://purl.bioontology.org/ontology/VANDF/4025779 VANDF CUI
http://purl.bioontology.org/ontology/MSHFRE/D000622 MSHFRE CUI
http://purl.bioontology.org/ontology/NDFRT/N0000176068 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/409398000 SCTSPA CUI
http://www.drugbank.ca/drugs/DB00855 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0002038 OMIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C234 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.262 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D000622 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1017 OCHV LOOM
http://purl.obolibrary.org/obo/DRON_00010084 PDRO LOOM
http://purl.jp/bio/4/id/200906056693313556 IOBC LOOM
http://purl.jp/bio/4/id/200906012277083560 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002563 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/683 RXNORM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016580 PMAPP-PMO LOOM
https://go.drugbank.com/drugs/DB00855 MDM LOOM
http://purl.bioontology.org/ontology/ATC/L01XD04 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C234 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.755.547.276 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#AminolevulinicAcid GALEN LOOM
http://purl.bioontology.org/ontology/VANDF/4025779 VANDF LOOM
http://purl.obolibrary.org/obo/MESH_D000622 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176068 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000622 RH-MESH LOOM