Preferred Name |
glimepiride |
|
Synonyms |
Amaryl |
|
Definitions |
A long-acting, third-generation sulfonylurea with hypoglycemic activity. Compared to other generations of sulfonylurea compounds, glimepiride is very potent and has a longer duration of action. This agent is metabolized by CYP2C9 and shows peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29073" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29073" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000775349 |
|
altLabel |
Amaryl |
|
CAS Registry |
93479-97-1 |
|
cui |
C0595112 C0061323 |
|
DATE FIRST PUBLISHED |
2015-09-04 |
|
Date last modified |
2015-09-03 |
|
definition |
A long-acting, third-generation sulfonylurea with hypoglycemic activity. Compared to other generations of sulfonylurea compounds, glimepiride is very potent and has a longer duration of action. This agent is metabolized by CYP2C9 and shows peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29073" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29073" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C29073 |
|
notation |
CDR0000775349 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
glimepiride |
|
tui |
T109 T121 |