Link to this page
Physician Data Query
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000750171
http://purl.bioontology.org/ontology/PDQ/CDR0000750171
|
---|---|
Preferred Name | lanreotide acetate |
Definitions |
The acetate salt of a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compared to octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C74584" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74584" NCI Thesaurus)
|
Synonyms |
Somatuline Depot
AT-1001
L-threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfide, acetate
|
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | The acetate salt of a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compared to octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C74584" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74584" NCI Thesaurus) |
---|---|
altLabel |
Somatuline Depot
AT-1001
L-threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfide, acetate
|
prefLabel |
lanreotide acetate
|
CAS Registry |
127984-74-1
|
notation |
CDR0000750171
|
ORIG STY |
Drug/agent
|
Date last modified |
2013-06-05
|
Semantic type UMLS property | |
NCI ID |
C74584
|
type | |
LT |
TRD
|
tui |
T109
T116
T123
T121
|
DATE FIRST PUBLISHED |
2013-06-05
|
cui |
C1999871
C1964933
C0771414
|
Delete | Subject | Author | Type | Created |
---|---|---|---|---|
No notes to display |