loading...| Preferred Name |
desmopressin acetate |
|
| Synonyms |
1-(3-mercaptopropionic acid)-8-D-arginine vasopression monoacetate |
|
| Definitions |
An analogue of the hormone vasopressin with antidiuretic and antihemorrhagic properties. Desmopressin acetate has selective affinity for the V2 receptor and acts on the distal kidney tubule by increasing the cellular permeability thereby stimulating water reabsorption. This antidiuretic agent is used in the treatment of central diabetes insipidus. An unrelated action of desmopressin acetate is to increases circulating factor VIII and is used in patients with haemophilia and von Willebrand's disease. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47475" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47475" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000734496 |
|
| altLabel |
1-(3-mercaptopropionic acid)-8-D-arginine vasopression monoacetate Stimate Concentraid Octostim DDAVP |
|
| CAS Registry |
62357-86-2 |
|
| cui |
C1330542 C0086135 C0701195 C1707693 |
|
| DATE FIRST PUBLISHED |
2012-05-29 |
|
| Date last modified |
2012-05-29 |
|
| definition |
An analogue of the hormone vasopressin with antidiuretic and antihemorrhagic properties. Desmopressin acetate has selective affinity for the V2 receptor and acts on the distal kidney tubule by increasing the cellular permeability thereby stimulating water reabsorption. This antidiuretic agent is used in the treatment of central diabetes insipidus. An unrelated action of desmopressin acetate is to increases circulating factor VIII and is used in patients with haemophilia and von Willebrand's disease. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47475" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47475" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47475 |
|
| notation |
CDR0000734496 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
desmopressin acetate |
|
| tui |
T125 T116 T121 |