Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

lipegfilgrastim
Synonyms

XM22

Definitions

A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, lipegfilgrastim has a prolonged plasma half-life. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C101778" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C101778" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000732856

altLabel

XM22

cui

C3640212

C4083253

DATE FIRST PUBLISHED

2012-04-30

Date last modified

2012-05-31

definition

A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, lipegfilgrastim has a prolonged plasma half-life. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C101778" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C101778" NCI Thesaurus)

NCI ID

C101778

notation

CDR0000732856

ORIG STY

Drug/agent

prefLabel

lipegfilgrastim

tui

T116

T129

T121

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