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Physician Data Query
| Id | http://purl.bioontology.org/ontology/PDQ/CDR0000712787
http://purl.bioontology.org/ontology/PDQ/CDR0000712787
|
|---|---|
| Preferred Name | nevirapine |
| Definitions |
A non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against human immunodeficiency virus 1. Nevirapine binds directly to the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29277" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29277" NCI Thesaurus)
|
| Synonyms |
BIRG 0587
NVP
11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
Viramune
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against human immunodeficiency virus 1. Nevirapine binds directly to the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29277" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29277" NCI Thesaurus) |
|---|---|
| altLabel |
BIRG 0587
NVP
11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
Viramune
|
| prefLabel |
nevirapine
|
| CAS Registry |
129618-40-2
|
| notation |
CDR0000712787
|
| NSC Code |
641530
|
| ORIG STY |
Drug/agent
|
| Date last modified |
2011-09-26
|
| Semantic type UMLS property | |
| NCI ID |
C29277
|
| type | |
| LT |
TRD
|
| tui |
T109
T114
T121
|
| DATE FIRST PUBLISHED |
2011-09-26
|
| cui |
C0733416
C0132326
C0728726
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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