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Physician Data Query
Last uploaded:
August 28, 2024
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| Preferred Name | carvedilol | |
| Synonyms |
Coreg |
|
| Definitions |
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000700417 |
|
| altLabel |
Coreg
|
|
| CAS Registry |
72956-09-3
|
|
| cui |
C0719509 C0054836
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|
| DATE FIRST PUBLISHED |
2011-05-10
|
|
| Date last modified |
2011-05-10
|
|
| definition |
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade.
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|
| LT |
TRD
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|
| notation |
CDR0000700417
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|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
carvedilol
|
|
| tui |
T109 T121
|
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