loading...| Preferred Name | dexpanthenol cream | |
| Synonyms |
d-pantothenol dexpanthenol pantenyl D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide provitamin B5 302962 motilyn Bepanthenol Ilopan D-pantothenyl alcohol |
|
| Definitions |
An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47481" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47481" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000675455 |
|
| altLabel |
d-pantothenol dexpanthenol pantenyl D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide provitamin B5 302962 motilyn Bepanthenol Ilopan D-pantothenyl alcohol |
|
| CAS Registry |
81-13-0 |
|
| cui |
C4733173 C4733172 C0721041 C0057610 |
|
| DATE FIRST PUBLISHED |
2010-06-11 |
|
| Date last modified |
2010-10-22 |
|
| definition |
An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47481" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47481" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47481 |
|
| notation |
CDR0000675455 |
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| ORIG STY |
Drug/agent |
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| prefLabel |
dexpanthenol cream |
|
| tui |
T109 T127 T121 |