Physician Data Query

Last uploaded: August 27, 2019
Id http://purl.bioontology.org/ontology/PDQ/CDR0000613648
http://purl.bioontology.org/ontology/PDQ/CDR0000613648
Preferred Name

high grade prostatic intraepithelial neoplasia

Definitions
Prostatic intraepithelial neoplasia characterized by the presence of morphologically malignant cells lining the acini and ducts. The malignant cells are enlarged, contain prominent nucleoli, and have increased nuclear/cytoloplasmic ratio. The malignant cells may grow within the ducts and acini in four architectural patterns: flat, tufting, micropapillary, and cribriform. The presence of high grade prostatic intraepithelial neoplasia in needle biopsy is a risk factor for the subsequent detection of carcinoma on repeat biopsy. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C5541" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C5541" NCI Thesaurus)
Synonyms
HGPIN
High-Grade Intraepithelial Neoplasia of Prostate
High-Grade Intraepithelial Neoplasia of the Prostate
High-Grade PIN
Type http://www.w3.org/2002/07/owl#Class
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