Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

Brassica vegetable
Synonyms
Definitions

A vegetable belonging to the Brassica genus of plants in the mustard family with potential chemopreventive activity. Brassica vegetables, including broccoli, cabbage, kale, Brussel sprouts, turnip and cauliflower, contain a significant amount of glucosinolates. Glucosinolate metabolites, such as sulforaphane and indole-3-carbinol, act as antioxidants and may stimulate endogenous phase II detoxifying enzymes, including glutathione S-transferase and quinone reductase. These biotransformation enzymes play major roles in the detoxification of carcinogenic agents. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73795" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73795" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000586659

cui

C0453113

DATE FIRST PUBLISHED

2008-01-31

Date last modified

2008-06-27

definition

A vegetable belonging to the Brassica genus of plants in the mustard family with potential chemopreventive activity. Brassica vegetables, including broccoli, cabbage, kale, Brussel sprouts, turnip and cauliflower, contain a significant amount of glucosinolates. Glucosinolate metabolites, such as sulforaphane and indole-3-carbinol, act as antioxidants and may stimulate endogenous phase II detoxifying enzymes, including glutathione S-transferase and quinone reductase. These biotransformation enzymes play major roles in the detoxification of carcinogenic agents. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73795" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73795" NCI Thesaurus)

NCI ID

C73795

notation

CDR0000586659

ORIG STY

Drug/agent

prefLabel

Brassica vegetable

tui

T168

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