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Physician Data Query
Last uploaded:
August 28, 2024
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| Preferred Name | famotidine | |
| Synonyms |
Pepcid Pepcid AC |
|
| Definitions |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29045" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29045" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000574268 |
|
| altLabel |
Pepcid Pepcid AC
|
|
| CAS Registry |
76824-35-6
|
|
| cui |
C0678119 C0591964 C0015620
|
|
| DATE FIRST PUBLISHED |
2007-10-24
|
|
| Date last modified |
2007-10-24
|
|
| definition |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29045" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29045" NCI Thesaurus)
|
|
| LT |
TRD
|
|
| NCI ID |
C29045
|
|
| notation |
CDR0000574268
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
famotidine
|
|
| tui |
T109 T121
|
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