loading...| Preferred Name |
povidone-iodine solution |
|
| Synonyms |
E-Z Prep |
|
| Definitions |
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the povoiodine-iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytosplasmic and membrane compounds. This agent exhbits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses.Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C766" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C766" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000539730 |
|
| altLabel |
E-Z Prep PVP iodine iodopovidone solution Betadine topical Traumasept Betaisodona Ultradine Betadine Betadine Solution Videne E-Z Scrub iodine povidone topical |
|
| CAS Registry |
25655-41-8 |
|
| cui |
C2825144 C1882431 C3215443 C1882432 C0699524 C0699526 C3226297 C2825143 C0731011 C0305458 C0032857 C2347652 |
|
| DATE FIRST PUBLISHED |
2007-03-22 |
|
| Date last modified |
2016-03-01 |
|
| definition |
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the povoiodine-iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytosplasmic and membrane compounds. This agent exhbits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses.Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C766" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C766" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C766 |
|
| notation |
CDR0000539730 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
povidone-iodine solution |
|
| tui |
T109 T200 T121 |