Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

eicosapentaenoic acid
Synonyms

all cis-5,8,11,14,17-eicosapentaenoic acid

IPA

timnodonic acid

icosapentaenoic acid

EPA
Definitions

An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C67080" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67080" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000537376
altLabel

all cis-5,8,11,14,17-eicosapentaenoic acid

IPA

timnodonic acid

icosapentaenoic acid

EPA
cui

C0000545
DATE FIRST PUBLISHED

2007-02-16
Date last modified

2008-04-24
definition

An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C67080" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67080" NCI Thesaurus)
NCI ID

C67080
notation

CDR0000537376
ORIG STY

Drug/agent
prefLabel

eicosapentaenoic acid
tui

T109

T123

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/MSHFRE/D015118 MSHFRE CUI
http://purl.bioontology.org/ontology/SNOMEDCT/763707009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDDF/002052 NDDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000004740 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D015118 MESH CUI
http://purl.bioontology.org/ontology/SCTSPA/226367006 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/226367006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/VANDF/4020139 VANDF CUI
http://purl.bioontology.org/ontology/RCD/Ub08v RCD CUI
http://purl.bioontology.org/ontology/CSP/1130-1983 CRISP CUI
http://purl.bioontology.org/ontology/RXNORM/90 RXNORM CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148114 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/763707009 SCTSPA CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.627.430.450.390 RH-MESH LOOM
http://doe-generated-ontology.com/OntoAD#C0000545 ONTOAD LOOM
http://purl.obolibrary.org/obo/MESH_D015118 BERO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03028 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03028 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03028 MIO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.251.355.337.290 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015118 RH-MESH LOOM
http://www.semanticweb.org/d.rastogi/ontologies/2024/1/altproton#EicosapentaenoicAcid ALTPROTON LOOM
http://purl.jp/bio/4/id/200906039536756604 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002052 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.251.355.255.200 RH-MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0000545 HFO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0000545 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D015118 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/226367006 SNOMEDCT LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass4ee2843e_d5b2_42a8_8c9f_cb77ca59a587 WWECA LOOM
http://id.nlm.nih.gov/mesh/D015118 MDM LOOM
http://purl.bioontology.org/ontology/VANDF/4020139 VANDF LOOM
http://www.co-ode.org/ontologies/galen#EicosapentaenoicAcid GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/90 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907061079626154 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.212.302.380.410.385 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0015935 OMIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148114 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#516 OCHV LOOM
http://bmi.utah.edu/ontologies/peontology/C0000545 RAO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67080 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021078 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C67080 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_36006 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_36006 ONSTR LOOM