An intermediate cutaneous fibrohistiocytic neoplasm, presenting as a nodular cutaneous mass, most often on the trunk and the proximal extremities. The tumor diffusely infiltrates the dermis and the subcutaneous tissues. It is considered a locally aggressive neoplasm, which often recurs but rarely metastasizes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C4683" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C4683" NCI Thesaurus)