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| Preferred Name | triptorelin pamoate | |
| Synonyms |
6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt) Pamorelin Trelstar Depot Diphereline |
|
| Definitions |
The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29523" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29523" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000468834 |
|
| altLabel |
6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt) Pamorelin Trelstar Depot Diphereline
|
|
| CAS Registry |
124508-66-3
|
|
| cui |
C0939509 C1137102 C4287824 C4721745
|
|
| DATE FIRST PUBLISHED |
2006-02-21
|
|
| Date last modified |
2016-07-20
|
|
| definition |
The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29523" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29523" NCI Thesaurus)
|
|
| LT |
TRD
|
|
| NCI ID |
C29523
|
|
| notation |
CDR0000468834
|
|
| NSC Code |
724666
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
triptorelin pamoate
|
|
| tui |
T125 T116 T121
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