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| Preferred Name | recombinant interferon alpha-2a | |
| Synonyms |
Roceron-A alpha 2 interferon Roferon-A Laroferon interferon alfa 2a IFN alpha-2A interferon alfa-2a rHuIFN-a 2a recombinant interferon alfa-2a IFN-alpha 2 |
|
| Definitions |
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1952" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1952" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000467189 |
|
| altLabel |
Roceron-A alpha 2 interferon Roferon-A Laroferon interferon alfa 2a IFN alpha-2A interferon alfa-2a rHuIFN-a 2a recombinant interferon alfa-2a IFN-alpha 2
|
|
| CAS Registry |
76543-88-9
|
|
| cui |
C0699179 C0021734 C1512831 C1512832
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|
| DATE FIRST PUBLISHED |
2006-02-21
|
|
| Date last modified |
2017-12-14
|
|
| definition |
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1952" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1952" NCI Thesaurus)
|
|
| LT |
TRD
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|
| NCI ID |
C1952
|
|
| notation |
CDR0000467189
|
|
| NSC Code |
367982
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|
| ORIG STY |
Drug/agent
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|
| prefLabel |
recombinant interferon alpha-2a
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|
| tui |
T116 T129 T121
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