loading...| Preferred Name |
ropivacaine hydrochloride |
|
| Synonyms |
Naropin |
|
| Definitions |
The hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. Ropivacaine binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions and resulting in. a stabilization of the neuronal membrane and inhibition of depolarization; nerve impulse generation and propagation are blocked, resulting in a reversible loss of sensation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52198" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52198" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000459953 |
|
| altLabel |
Naropin ropivacaine hydrochloride monohydrate |
|
| cui |
C1882959 C0525803 C0771826 |
|
| DATE FIRST PUBLISHED |
2005-12-22 |
|
| Date last modified |
2015-05-14 |
|
| definition |
The hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. Ropivacaine binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions and resulting in. a stabilization of the neuronal membrane and inhibition of depolarization; nerve impulse generation and propagation are blocked, resulting in a reversible loss of sensation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52198" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52198" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C52198 |
|
| notation |
CDR0000459953 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
ropivacaine hydrochloride |
|
| tui |
T109 T121 |