loading...| Preferred Name | oxitriptan | |
| Synonyms |
5-HTP 5-hydroxytryptophan 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid |
|
| Definitions |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous 5-hydroxytryptophan (5-HTP) is produced from the essential amino acid L-tryptophan. Exogenous therapeutic 5-HTP is isolated from the seeds of the African plant Griffonia simplicifolia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52181" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52181" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000459776 |
|
| altLabel |
5-HTP 5-hydroxytryptophan 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid |
|
| cui |
C0000578 |
|
| DATE FIRST PUBLISHED |
2005-12-22 |
|
| Date last modified |
2010-10-27 |
|
| definition |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous 5-hydroxytryptophan (5-HTP) is produced from the essential amino acid L-tryptophan. Exogenous therapeutic 5-HTP is isolated from the seeds of the African plant Griffonia simplicifolia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52181" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52181" NCI Thesaurus) |
|
| NCI ID |
C52181 |
|
| notation |
CDR0000459776 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
oxitriptan |
|
| tui |
T116 T123 T121 |