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Physician Data Query
| Preferred Name | palifermin | |
| Synonyms |
rhKGF recombinant human keratinocyte growth factor rHuKGF rhu keratinocyte growth factor Kepivance keratinocyte growth factor, recombinant human growth factor, recombinant human keratinocyte |
|
| Definitions |
A recombinant form of the endogenous human keratinocyte growth factor. Palifermin binds to epithelial cell surface receptors in the lining of the mouth and gastrointestinal tract, resulting in stimulation of epithelial cell proliferation, differentiation and upregulation of cytoprotective mechanisms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2455" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2455" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042905 |
|
| altLabel |
rhKGF recombinant human keratinocyte growth factor rHuKGF rhu keratinocyte growth factor Kepivance keratinocyte growth factor, recombinant human growth factor, recombinant human keratinocyte
|
|
| cui |
C0677829 C1589890
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|
| Date last modified |
2010-05-20
|
|
| definition |
A recombinant form of the endogenous human keratinocyte growth factor. Palifermin binds to epithelial cell surface receptors in the lining of the mouth and gastrointestinal tract, resulting in stimulation of epithelial cell proliferation, differentiation and upregulation of cytoprotective mechanisms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2455" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2455" NCI Thesaurus)
|
|
| Legacy PDQ ID |
6736
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|
| LT |
TRD
|
|
| NCI ID |
C2455
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|
| notation |
CDR0000042905
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| ORIG STY |
Drug/agent
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|
| prefLabel |
palifermin
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|
| tui |
T116 T121
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