Physician Data Query - trastuzumab - Classes | NCBO BioPortal

Physician Data Query

Last uploaded: August 27, 2019

Id	http://purl.bioontology.org/ontology/PDQ/CDR0000042265 http://purl.bioontology.org/ontology/PDQ/CDR0000042265
Preferred Name	trastuzumab
Definitions	A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1647" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1647" NCI Thesaurus)
Synonyms	RO0452317 trastuzumab biosimilar ABP 980 ABP 980 anti-c-erbB2 monoclonal antibody anti-c-erB-2 anti-HER2/c-erbB2 monoclonal antibody MOAB HER2 anti-erbB-2 Herceptin monoclonal antibody c-erb-2 HER2 monoclonal antibody trastuzumab biosimilar ALT02 anti-erbB2 monoclonal antibody PF-05280014 Herceptin biosimilar PF-05280014 trastuzumab biosimilar HLX02 trastuzumab biosimilar PF-05280014 monoclonal antibody HER2 trastuzumab biosimilar SB3 rhuMAb HER2 Ogivri anti-p185-HER2 anti-ERB-2 Herceptin trastuzumab biosimilar PF-05280014 See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1647" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1647" NCI Thesaurus)
altLabel	RO0452317 trastuzumab biosimilar ABP 980 ABP 980 anti-c-erbB2 monoclonal antibody anti-c-erB-2 anti-HER2/c-erbB2 monoclonal antibody MOAB HER2 anti-erbB-2 Herceptin monoclonal antibody c-erb-2 HER2 monoclonal antibody trastuzumab biosimilar ALT02 anti-erbB2 monoclonal antibody PF-05280014 Herceptin biosimilar PF-05280014 trastuzumab biosimilar HLX02 trastuzumab biosimilar PF-05280014 monoclonal antibody HER2 trastuzumab biosimilar SB3 rhuMAb HER2 Ogivri anti-p185-HER2 anti-ERB-2 Herceptin trastuzumab biosimilar PF-05280014 See more See less
prefLabel	trastuzumab
notation	CDR0000042265
NSC Code	688097
ORIG STY	Drug/agent
Component of	http://purl.bioontology.org/ontology/PDQ/CDR0000352312 http://purl.bioontology.org/ontology/PDQ/CDR0000042466 http://purl.bioontology.org/ontology/PDQ/CDR0000038369 http://purl.bioontology.org/ontology/PDQ/CDR0000038436 http://purl.bioontology.org/ontology/PDQ/CDR0000391853 http://purl.bioontology.org/ontology/PDQ/CDR0000378335 http://purl.bioontology.org/ontology/PDQ/CDR0000372882 http://purl.bioontology.org/ontology/PDQ/CDR0000037973 http://purl.bioontology.org/ontology/PDQ/CDR0000037969 http://purl.bioontology.org/ontology/PDQ/CDR0000037855 http://purl.bioontology.org/ontology/PDQ/CDR0000038404 http://purl.bioontology.org/ontology/PDQ/CDR0000038432 http://purl.bioontology.org/ontology/PDQ/CDR0000038435 http://purl.bioontology.org/ontology/PDQ/CDR0000038673 http://purl.bioontology.org/ontology/PDQ/CDR0000042465 http://purl.bioontology.org/ontology/PDQ/CDR0000043391 http://purl.bioontology.org/ontology/PDQ/CDR0000038695 http://purl.bioontology.org/ontology/PDQ/CDR0000371642 http://purl.bioontology.org/ontology/PDQ/CDR0000043253 http://purl.bioontology.org/ontology/PDQ/CDR0000038365 http://purl.bioontology.org/ontology/PDQ/CDR0000357418 http://purl.bioontology.org/ontology/PDQ/CDR0000426427 http://purl.bioontology.org/ontology/PDQ/CDR0000038640 http://purl.bioontology.org/ontology/PDQ/CDR0000361548 http://purl.bioontology.org/ontology/PDQ/CDR0000288843 http://purl.bioontology.org/ontology/PDQ/CDR0000373802 http://purl.bioontology.org/ontology/PDQ/CDR0000043558 http://purl.bioontology.org/ontology/PDQ/CDR0000038009 http://purl.bioontology.org/ontology/PDQ/CDR0000038077 http://purl.bioontology.org/ontology/PDQ/CDR0000038107 http://purl.bioontology.org/ontology/PDQ/CDR0000038661 http://purl.bioontology.org/ontology/PDQ/CDR0000037990 http://purl.bioontology.org/ontology/PDQ/CDR0000038304 http://purl.bioontology.org/ontology/PDQ/CDR0000038062 http://purl.bioontology.org/ontology/PDQ/CDR0000042266 http://purl.bioontology.org/ontology/PDQ/CDR0000445586 http://purl.bioontology.org/ontology/PDQ/CDR0000038518 http://purl.bioontology.org/ontology/PDQ/CDR0000043564 http://purl.bioontology.org/ontology/PDQ/CDR0000256419 http://purl.bioontology.org/ontology/PDQ/CDR0000038261 http://purl.bioontology.org/ontology/PDQ/CDR0000038594 http://purl.bioontology.org/ontology/PDQ/CDR0000370025 http://purl.bioontology.org/ontology/PDQ/CDR0000037876 http://purl.bioontology.org/ontology/PDQ/CDR0000329986 http://purl.bioontology.org/ontology/PDQ/CDR0000038364 http://purl.bioontology.org/ontology/PDQ/CDR0000373961 See more See less
Legacy PDQ ID	5512
Date last modified	2018-07-26
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T129 http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T116 http://purl.bioontology.org/ontology/STY/T109
NCI ID	C1647
type	http://www.w3.org/2002/07/owl#Class
IND Code	6667
LT	TRD
tui	T109 T116 T129 T121
cui	C0728747 C3887778 C4721641 C3887777 C0338204 C4087073 C4727806 C4727807 C4732952 See more See less

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