Physician Data Query

Last uploaded: August 27, 2019
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Preferred Name

daclizumab
Synonyms

Anti-Tac Humanized Monoclonal Antibody

humanized anti-Tac monoclonal antibody

monoclonal antibody anti-Tac

Zenapax

MOAB anti-Tac

monoclonal antibody humanized anti-Tac

Dacliximab

anti-Tac monoclonal antibody

anti-Tac
Definitions

A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2 (IL-2) receptor expressed on the surface of activated lymphocytes in vivo, thereby inhibiting IL-2 binding and IL-2-mediated lymphocyte activation, a critical cellular immune response pathway. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1569" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1569" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000042006
altLabel

Anti-Tac Humanized Monoclonal Antibody

humanized anti-Tac monoclonal antibody

monoclonal antibody anti-Tac

Zenapax

MOAB anti-Tac

monoclonal antibody humanized anti-Tac

Dacliximab

anti-Tac monoclonal antibody

anti-Tac
CAS Registry

152923-56-3
Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000043354

http://purl.bioontology.org/ontology/PDQ/CDR0000271170
cui

C0663182

C0281549
Date last modified

2006-08-01
definition

A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2 (IL-2) receptor expressed on the surface of activated lymphocytes in vivo, thereby inhibiting IL-2 binding and IL-2-mediated lymphocyte activation, a critical cellular immune response pathway. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1569" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1569" NCI Thesaurus)
IND Code

2091
Legacy PDQ ID

5231
LT

TRD
NCI ID

C1569
notation

CDR0000042006
ORIG STY

Drug/agent
prefLabel

daclizumab
tui

T116

T129

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/RXNORM/190353 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D000077561 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148541 NDFRT CUI
http://purl.bioontology.org/ontology/ATC/L04AC01 ATC CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077561 MSHFRE CUI
http://purl.bioontology.org/ontology/SCTSPA/109133001 SCTSPA CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005792 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4021083 VANDF CUI
http://purl.bioontology.org/ontology/SCTSPA/386977009 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/007284 NDDF CUI
http://purl.bioontology.org/ontology/MESH/D000077561 MESH CUI
http://purl.bioontology.org/ontology/SNOMEDCT/386977009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/109133001 SNOMEDCT CUI
http://purl.bioontology.org/ontology/RXNORM/190353 RXNORM LOOM
http://purl.obolibrary.org/obo/DRON_00013001 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00013001 DDSS LOOM
http://purl.obolibrary.org/obo/DRON_00013001 DRON LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148541 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/L04AC01 ATC LOOM
http://purl.jp/bio/4/id/200906003374990727 IOBC LOOM
http://www.drugbank.ca/drugs/DB00111 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1569 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0663182 OCHV LOOM
http://scai.fraunhofer.de/MSOntology#Daclizumab MSO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026129 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C1569 BERO LOOM
https://go.drugbank.com/drugs/DB00111 MDM LOOM
http://purl.bioontology.org/ontology/VANDF/4021083 VANDF LOOM
http://purl.obolibrary.org/obo/dinto_DB00111 DINTO LOOM
http://purl.bioontology.org/ontology/MESH/D000077561 MESH LOOM
http://www.co-ode.org/ontologies/galen#Daclizumab GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#42521 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C096001 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386977009 SNOMEDCT LOOM