loading...| Preferred Name |
primary systemic amyloidosis |
|
| Synonyms |
systemic amyloidosis, primary systemic amyloidosis systemic AL amyloidosis systemic immunoglobulin light chain amyloidosis amyloidosis, primary systemic |
|
| Definitions |
A plasma cell neoplasm that secretes an abnormal immunoglobulin, which deposits in various tissues and forms a beta-pleated sheet structure that binds Congo red dye with characteristic birefringence. The sites of involvement include heart, liver, kidney, gut, tongue, nerves, and bone. (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C8299" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C8299" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041926 |
|
| altLabel |
systemic amyloidosis, primary systemic amyloidosis systemic AL amyloidosis systemic immunoglobulin light chain amyloidosis amyloidosis, primary systemic |
|
| cui |
C0281479 |
|
| Date last modified |
2017-12-11 |
|
| definition |
A plasma cell neoplasm that secretes an abnormal immunoglobulin, which deposits in various tissues and forms a beta-pleated sheet structure that binds Congo red dye with characteristic birefringence. The sites of involvement include heart, liver, kidney, gut, tongue, nerves, and bone. (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C8299" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C8299" NCI Thesaurus) |
|
| Legacy PDQ ID |
5146 |
|
| MENU PARENT |
multiple myeloma and other plasma cell neoplasms |
|
| MENU TYPE |
Clinical Trials--CancerType |
|
| NCI ID |
C8299 |
|
| notation |
CDR0000041926 |
|
| ORIG STY |
Cancer stage |
|
| prefLabel |
primary systemic amyloidosis |
|
| tui |
T191 |
|
| subClassOf |