gamma-interferon

gamma interferon

IFN-G

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C583" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C583" NCI Thesaurus)

http://purl.bioontology.org/ontology/PDQ/CDR0000040469

http://purl.bioontology.org/ontology/PDQ/CDR0000041249

http://purl.bioontology.org/ontology/PDQ/CDR0000041304

http://purl.bioontology.org/ontology/PDQ/CDR0000040883

http://purl.bioontology.org/ontology/PDQ/CDR0000043679

http://purl.bioontology.org/ontology/PDQ/CDR0000038061

http://purl.bioontology.org/ontology/PDQ/CDR0000042457

http://purl.bioontology.org/ontology/PDQ/CDR0000041667

http://purl.bioontology.org/ontology/PDQ/CDR0000042861

http://purl.bioontology.org/ontology/PDQ/CDR0000042058

http://purl.bioontology.org/ontology/PDQ/CDR0000038843

http://purl.bioontology.org/ontology/PDQ/CDR0000041706

http://purl.bioontology.org/ontology/PDQ/CDR0000304319

http://purl.bioontology.org/ontology/PDQ/CDR0000042390

http://purl.bioontology.org/ontology/PDQ/CDR0000039670

http://purl.bioontology.org/ontology/PDQ/CDR0000042557

http://purl.bioontology.org/ontology/PDQ/CDR0000041998

http://purl.bioontology.org/ontology/PDQ/CDR0000041116

http://purl.bioontology.org/ontology/PDQ/CDR0000356027

http://purl.bioontology.org/ontology/PDQ/CDR0000355635

http://purl.bioontology.org/ontology/PDQ/CDR0000041426

http://purl.bioontology.org/ontology/PDQ/CDR0000040884