loading...| Preferred Name |
recombinant tumor necrosis factor family protein |
|
| Synonyms |
TNF tumor necrosis factor Tumor Necrosis Factors Tumor Necrosis Factor Family Protein |
|
| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1941" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1941" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040250 |
|
| altLabel |
TNF tumor necrosis factor Tumor Necrosis Factors Tumor Necrosis Factor Family Protein |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000041201 http://purl.bioontology.org/ontology/PDQ/CDR0000039642 http://purl.bioontology.org/ontology/PDQ/CDR0000042028 http://purl.bioontology.org/ontology/PDQ/CDR0000041467 http://purl.bioontology.org/ontology/PDQ/CDR0000039091 http://purl.bioontology.org/ontology/PDQ/CDR0000042098 http://purl.bioontology.org/ontology/PDQ/CDR0000040999 http://purl.bioontology.org/ontology/PDQ/CDR0000041706 http://purl.bioontology.org/ontology/PDQ/CDR0000042059 http://purl.bioontology.org/ontology/PDQ/CDR0000042557 http://purl.bioontology.org/ontology/PDQ/CDR0000041998 http://purl.bioontology.org/ontology/PDQ/CDR0000040509 |
|
| cui |
C1522668 C0041368 |
|
| Date last modified |
2007-02-19 |
|
| definition |
A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1941" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1941" NCI Thesaurus) |
|
| Legacy PDQ ID |
3078 |
|
| NCI ID |
C1941 |
|
| notation |
CDR0000040250 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
recombinant tumor necrosis factor family protein |
|
| tui |
T116 T129 |