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Physician Data Query
Acronym | PDQ |
Visibility | Public |
Description | Physician Data Query (PDQ) Terminology is part of NCI's comprehensive cancer information database, which contains expert summaries on a wide range of cancer topics, a listing of some 30,000 cancer clinical trials from around the world, a directory of genetics services professionals, the NCI Dictionary of Cancer Terms, and the NCI Drug Dictionary. |
Status | Production |
Format | UMLS |
Contact | Volker Englisch, volker@mail.nih.gov |
Categories | Health |
Groups | Unified Medical Language System |
License Information | This ontology is made available via the UMLS. Users of all UMLS ontologies must abide by the terms of the UMLS license. |
Version | Released | Uploaded | Downloads |
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PDQ_2018_10_27 (Parsed, Indexed, Metrics, Annotator) | 05/06/2019 | 08/27/2019 | RDF/TTL | CSV | Diff |
2018AB (Archived) | 11/05/2018 | 04/29/2019 | RDF/TTL | Diff |
2018AA (Archived) | 05/07/2018 | 07/06/2018 | RDF/TTL | Diff |
2017AB (Archived) | 11/06/2017 | 07/06/2018 | RDF/TTL | Diff |
2017AA (Archived) | 05/08/2017 | 04/06/2018 | RDF/TTL | Diff |
2016AB (Archived) | 02/06/2017 | 02/06/2017 | RDF/TTL | Diff |
2016AA (Archived) | 09/06/2016 | 09/06/2016 | RDF/TTL | Diff |
2015AB (Archived) | 07/20/2016 | 07/20/2016 | RDF/TTL | Diff |
2015AA (Archived) | 06/09/2015 | 06/09/2015 | RDF/TTL | Diff |
2014AB (Archived) | 01/29/2015 | 01/29/2015 | RDF/TTL | Diff |
2014AA (Archived) | 05/28/2014 | 05/28/2014 | RDF/TTL | Diff |
2013AB (Archived) | 02/18/2014 | 02/18/2014 | RDF/TTL | Diff |
2013AA (Archived) | 01/14/2014 | 01/14/2014 | RDF/TTL | Diff |
2013AA (Archived) | 05/08/2013 | 09/25/2013 | RDF/TTL | Diff |
2010_04_09 (Archived) | 04/09/2010 | 11/18/2010 | RDF/TTL |
2007_02 (Archived) | 02/01/2007 | 07/31/2009 | RDF/TTL |
more... |
No views of PDQ available
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000039547
http://purl.bioontology.org/ontology/PDQ/CDR0000039547
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Preferred Name | sparfosic acid |
Definitions |
A stable transition state analogue for an aspartate transcarbamylase- cartalyzed reaction with antineoplastic activity. Sparfosic acid is a stable transition analogue of the activated complex for the reaction catalyzed by aspartate transcarbamylase, the first step in the pyrimidine biosynthetic pathway. This agent inhibits de novo pyrimidine biosynthesis and increases the extent to which fluorouracil metabolites are incorporated into RNA. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1398" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1398" NCI Thesaurus)
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Synonyms |
sparfosate
N-phosphonacetyl-L-aspartate
PALA
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A stable transition state analogue for an aspartate transcarbamylase- cartalyzed reaction with antineoplastic activity. Sparfosic acid is a stable transition analogue of the activated complex for the reaction catalyzed by aspartate transcarbamylase, the first step in the pyrimidine biosynthetic pathway. This agent inhibits de novo pyrimidine biosynthesis and increases the extent to which fluorouracil metabolites are incorporated into RNA. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1398" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1398" NCI Thesaurus) |
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altLabel |
sparfosate
N-phosphonacetyl-L-aspartate
PALA
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prefLabel | sparfosic acid
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notation | CDR0000039547
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ORIG STY | Drug/agent
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Component of |
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Legacy PDQ ID | 2197
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Date last modified | 2010-10-27
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Semantic type UMLS property | |
NCI ID | C1398
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type | |
tui |
T109
T116
T121
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cui |
C0135096
C0069076
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