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Physician Data Query
Last uploaded:
August 27, 2019
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| Id | http://purl.bioontology.org/ontology/PDQ/CDR0000039240
http://purl.bioontology.org/ontology/PDQ/CDR0000039240
|
|---|---|
| Preferred Name | trifluridine |
| Definitions |
A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C905" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C905" NCI Thesaurus)
|
| Synonyms |
triflorothymidine
2'-Deoxy-5-trifluoromethyluridine
F3TdR
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C905" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C905" NCI Thesaurus) |
|---|---|
| altLabel |
triflorothymidine
2'-Deoxy-5-trifluoromethyluridine
F3TdR
|
| prefLabel |
trifluridine
|
| CAS Registry |
70-00-8
|
| notation |
CDR0000039240
|
| NSC Code |
75520
|
| ORIG STY |
Drug/agent
|
| Legacy PDQ ID |
1862
|
| Date last modified |
2006-12-12
|
| Semantic type UMLS property | |
| NCI ID |
C905
|
| type | |
| IND Code |
3953
|
| tui |
T114
T121
|
| cui |
C0040987
|
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