estramustine phosphate sodium

Emcyt

The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that combines estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C480" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C480" NCI Thesaurus)

http://purl.bioontology.org/ontology/PDQ/CDR0000039235

Emcyt

estra-1,3,5(10)-triene-3,17-diol(17(beta))-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt, monohydrate

Leo-299

estramustine sodium phosphate

estramustine 17-(dihydrogenphosphate) disodium salt

estramustine phosphate

Estracyt

Ro-21-8837/001

52205-73-9

http://purl.bioontology.org/ontology/PDQ/CDR0000363904

http://purl.bioontology.org/ontology/PDQ/CDR0000042809

http://purl.bioontology.org/ontology/PDQ/CDR0000363905

http://purl.bioontology.org/ontology/PDQ/CDR0000041756

http://purl.bioontology.org/ontology/PDQ/CDR0000357941

http://purl.bioontology.org/ontology/PDQ/CDR0000042813

http://purl.bioontology.org/ontology/PDQ/CDR0000037956

http://purl.bioontology.org/ontology/PDQ/CDR0000352014

http://purl.bioontology.org/ontology/PDQ/CDR0000357873

http://purl.bioontology.org/ontology/PDQ/CDR0000038446

http://purl.bioontology.org/ontology/PDQ/CDR0000042808

http://purl.bioontology.org/ontology/PDQ/CDR0000041849

http://purl.bioontology.org/ontology/PDQ/CDR0000038486

http://purl.bioontology.org/ontology/PDQ/CDR0000043257

http://purl.bioontology.org/ontology/PDQ/CDR0000041688

http://purl.bioontology.org/ontology/PDQ/CDR0000042219

http://purl.bioontology.org/ontology/PDQ/CDR0000043645

http://purl.bioontology.org/ontology/PDQ/CDR0000269167

http://purl.bioontology.org/ontology/PDQ/CDR0000363901

http://purl.bioontology.org/ontology/PDQ/CDR0000042705

http://purl.bioontology.org/ontology/PDQ/CDR0000370053

http://purl.bioontology.org/ontology/PDQ/CDR0000041762

http://purl.bioontology.org/ontology/PDQ/CDR0000038303

http://purl.bioontology.org/ontology/PDQ/CDR0000358327

http://purl.bioontology.org/ontology/PDQ/CDR0000041880

http://purl.bioontology.org/ontology/PDQ/CDR0000358199

http://purl.bioontology.org/ontology/PDQ/CDR0000042401

http://purl.bioontology.org/ontology/PDQ/CDR0000042633

http://purl.bioontology.org/ontology/PDQ/CDR0000358058

http://purl.bioontology.org/ontology/PDQ/CDR0000042387

http://purl.bioontology.org/ontology/PDQ/CDR0000358333

http://purl.bioontology.org/ontology/PDQ/CDR0000037931

http://purl.bioontology.org/ontology/PDQ/CDR0000043020

C0014922

C0013953

C0356799

C1521874

C1521873

C0014911

2017-10-30

The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that combines estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C480" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C480" NCI Thesaurus)

1857

TRD

C480

CDR0000039235

89199

Drug/agent

estramustine phosphate sodium

T109

T121