Preferred Name |
clopidogrel bisulfate |
|
Synonyms |
Plavix |
|
Definitions |
A thienopyridine with antiplatelet activity. Clopidogrel bisulfate irreversibly alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2673" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2673" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000038611 |
|
altLabel |
Plavix CLOBI |
|
Component of | ||
cui |
C0633084 C0772326 |
|
Date last modified |
2006-07-31 |
|
definition |
A thienopyridine with antiplatelet activity. Clopidogrel bisulfate irreversibly alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2673" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2673" NCI Thesaurus) |
|
Legacy PDQ ID |
11239 |
|
LT |
TRD |
|
NCI ID |
C2673 |
|
notation |
CDR0000038611 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
clopidogrel bisulfate |
|
tui |
T109 T121 |