loading...| Preferred Name |
interleukin-2 gene |
|
| Synonyms |
IL-2 gene |
|
| Definitions |
The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2549" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2549" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000038045 |
|
| altLabel |
IL-2 gene |
|
| Component of | ||
| cui |
C0879590 |
|
| Date last modified |
2006-08-28 |
|
| definition |
The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2549" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2549" NCI Thesaurus) |
|
| Legacy PDQ ID |
10565 |
|
| NCI ID |
C2549 |
|
| notation |
CDR0000038045 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
interleukin-2 gene |
|
| tui |
T028 |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/OMIM/147680 | OMIM | CUI | |
| http://purl.obolibrary.org/obo/NCIT_C2549 | BERO | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2549 | NCIT | LOOM |