Preferred Name |
enoxaparin sodium |
|
Synonyms |
Lovenox |
|
Definitions |
The sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C75769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C75769" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000037880 |
|
altLabel |
Lovenox |
|
CAS Registry |
679809-58-6 |
|
cui |
C0728963 C0724579 |
|
definition |
The sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C75769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C75769" NCI Thesaurus) |
|
Legacy PDQ ID |
10283 |
|
LT |
TRD |
|
NCI ID |
C75769 |
|
notation |
CDR0000037880 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
enoxaparin sodium |
|
tui |
T109 T121 |