Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

enoxaparin sodium

Synonyms

Lovenox

Definitions

The sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C75769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C75769" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000037880

altLabel

Lovenox

CAS Registry

679809-58-6

cui

C0728963

C0724579

definition

The sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C75769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C75769" NCI Thesaurus)

Legacy PDQ ID

10283

LT

TRD

NCI ID

C75769

notation

CDR0000037880

ORIG STY

Drug/agent

prefLabel

enoxaparin sodium

tui

T109

T121

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