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Parkinson's Disease Ontology
Last uploaded:
August 18, 2014
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| Id | http://www.semanticweb.org/ontologies/2011/1/Ontology1296772722296.owl#Manganese
http://www.semanticweb.org/ontologies/2011/1/Ontology1296772722296.owl#Manganese
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| Preferred Name | Manganese |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | Manganese
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| prefLabel | Manganese
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| isDefinedBy | Manganese can cause manganism, an irreversible neurological disorder similar to Parkinson's disease. Occupational exposures occur mainly in welding, mining as miners are surrounded by manganese dust and airborne manganese particles, alloy production, processing, ferro-manganese operations especially in which manganese ore or manganese compounds are turned into steel, and work with agrochemicals. The towns and communities surrounding the areas of manganese heavy industry could also become affected by toxic exposure to manganese. It is also hypothesized that long-term exposure to the naturally-occurring manganese in shower water also puts people at risk. Manganese inhibits tyrosine hydroxylation, which is essential for the formation of dopamine. So manganese may cause Parkinson's disease by lowering dopamine levels.
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| prefixIRI | Manganese
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| Reference | Jankovic, J. J. T. E., & Tolosa. (2007). Parkinson's disease and movement disorders. E. Tolosa (Ed.). Lippincott Williams & Wilkins.
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