Provisional Cell Ontology

Last uploaded: January 8, 2025
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Id http://purl.obolibrary.org/obo/UBERON_0000016
http://purl.obolibrary.org/obo/UBERON_0000016
Preferred Name

endocrine pancreas
Definitions
The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.
Synonyms
islets of Langerhans part of pancreas
endocrine part of pancreas
endocrine pancreas
pars endocrina pancreatis
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.
prefLabel
endocrine pancreas
label
endocrine pancreas
database_cross_reference
MESH:D007515
EMAPA:35305
SCTID:361339003
BTO:0000650
CALOHA:TS-1302
TAO:0001260
ZFA:0001260
EFO:0002542
NCIT:C32509
VHOG:0000049
Wikipedia:Islets_of_Langerhans
EV:0100129
FMA:16018
MA:0001582
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notation
UBERON:0000016
inSubset
editor note
create a separate class for distributed pancreas, eg cyclostomes?
has_related_synonym
islets of Langerhans part of pancreas
endocrine part of pancreas
id
UBERON:0000016
has part
hasOBONamespace
uberon
part_of
UBPROP_0000008
endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys
UBPROP_0000001
The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]
The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]
UBPROP_0000003
In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]
functionally related to
RO_0002175
capable of
capable of part of
subClassOf
overlaps
develops_from
composed primarily of
type
has_exact_synonym
endocrine pancreas
pars endocrina pancreatis
contributes to morphology of
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