Preferred Name |
Cisplatin |
|
Synonyms |
|
|
Definitions |
An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition./NCI-GLOSS Definition: A drug used to treat many types of cancer. Cisplatin contains the metal platinum. It kills cancer cells by damaging their DNA and stopping them from dividing. Cisplatin is a type of alkylating agent. |
|
ID |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Cisplatin |
|
ChineseLabel |
顺铂 |
|
definition |
An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition./NCI-GLOSS Definition: A drug used to treat many types of cancer. Cisplatin contains the metal platinum. It kills cancer cells by damaging their DNA and stopping them from dividing. Cisplatin is a type of alkylating agent. |
|
label |
Cisplatin |
|
prefixIRI |
ProstateCancer:Cisplatin |
|
prefLabel |
Cisplatin |
|
reference |
NCI Thesaurus Code:C376 |
|
synonyms |
Cis-platinum II Diamine Dichloride (SP-4-2)-Diamminedichloroplatinum Cis-platinous Diamine Dichloride Cis-diamminedichloridoplatinum Peyrone's Chloride Cis-platinum Citoplatino Cis-dichloroammine Platinum (II) Cis-platinum II Lederplatin Cis-diamminedichloroplatinum Cisplatinum Platinol- AQ Cis-diamminedichloro Platinum (II) Platiblastin Peyrone's Salt Abiplatin Blastolem Briplatin CDDP CISPLATIN Cismaplat Cisplatin Cisplatina Cisplatyl Citosin Cysplatyna Metaplatin Neoplatin Placis Plastistil Platamine Platinex Platinol Platosin cisplatin |
|
URL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C376 |
|
subClassOf |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Chemotherapy |