Link to this page
Prostate Cancer Ontology
| Preferred Name | Warfarin | |
| Synonyms |
|
|
| Definitions |
A synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. This inhibition results in a sequential depression of Factors VII, IX, X and II activities. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K dependent clotting factors. The vitamin promotes the biosynthesis of gamma-carboxyglutamic acid residues in these proteins which are essential for biological activity. NCI-GLOSS Definition: A drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners)." |
|
| ID |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Warfarin |
|
| ChineseLabel |
华法林
|
|
| definition |
A synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. This inhibition results in a sequential depression of Factors VII, IX, X and II activities. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K dependent clotting factors. The vitamin promotes the biosynthesis of gamma-carboxyglutamic acid residues in these proteins which are essential for biological activity.
NCI-GLOSS Definition: A drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners)."
|
|
| label |
Warfarin
|
|
| prefixIRI |
ProstateCancer:Warfarin
|
|
| prefLabel |
Warfarin
|
|
| reference |
NCI Thesaurus Code:C945
|
|
| synonyms |
Athrombin-K 3-(Alpha-acetonylbenzyl)-4-hydroxycoumarin 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one 3-Alpha-phenyl-beta-acetylethyl-4-hydroxycoumarin Compound 42 WARF Compound 42 3-(.alpha.-Acetonylbenzyl)-4-hydroxycoumarin WARF compound 42 3-(.alpha.-Phenyl-.beta.-acetylethyl)-4-hydroxycoumarin 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone Co-Rax Rodex WARFARIN Warfarin warfarin
|
|
| URL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C945
|
|
| subClassOf |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Drug |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |