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Prostate Cancer Ontology
Acronym | PCAO |
Visibility | Public |
Description | Here, we introduce the Prostate cancer ontology (PCaO) as a comprehensive semantic framework covering the whole breadth of the PCa’s knowledge domain. This ontology with a subclass-based taxonomic hierarchy not only covers the broad spectrum of major biomedical concepts from molecular to clinical features of the disease, but also the different views on disease features held by molecular biologists, clinicians and drug developers. PCaO organized under three biological viewpoints, i.e., epidemiology, diagnosis, and treatment. Note: The prostate cancer ontology version 1.0 (PCAO 1.0) was published by Hua Min in 2009 (PMID: 19497389). |
Status | Beta |
Format | OWL |
Contact | Chunjiang Yu, 743434289@qq.com Bairong Shen, bairong.shen@scu.edu.cn Qiang Wei , weiqiang933@126.com |
Categories | Health, Human |
No views of PCAO available
Id | http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Mitoxantrone
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Mitoxantrone
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Preferred Name | Mitoxantrone |
Definitions |
An anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin./NCI-GLOSS Definition: A drug used to treat advanced prostate cancer that does not respond to hormones, adult acute nonlymphocytic leukemia, and advanced or chronic multiple sclerosis. It is also being studied in the treatment of other cancers. It belongs to the family of drugs called antitumor antibiotics.
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | An anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin./NCI-GLOSS Definition: A drug used to treat advanced prostate cancer that does not respond to hormones, adult acute nonlymphocytic leukemia, and advanced or chronic multiple sclerosis. It is also being studied in the treatment of other cancers. It belongs to the family of drugs called antitumor antibiotics. |
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label | Mitoxantrone
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prefLabel | Mitoxantrone
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synonyms |
Dihydroxyanthracenedione
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthroquinone
1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione
MITOXANTRONE
Mitozantrone
Mitoxantrone
mitoxantrone
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URL | |
prefixIRI | ProstateCancer:Mitoxantrone
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subClassOf | |
reference | NCI Thesaurus Code:C62050
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type |
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- Problem retrieving properties:
Notes
Add NCBO Web Widgets to your site for PCAO
Widget type | Widget demonstration |
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Step 2: Follow the Instructions
For more help visit NCBO Widget Wiki |
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Example 1 (start typing the class name to get its full URI)
Example 2 (get the ID for a class) Example 3 (get the preferred name for a class) Step 2: Follow the Instructions
For more help visit NCBO Widget Wiki |
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <iframe frameborder="0" src="/widgets/visualization?ontology=PCAO&class=http%3A%2F%2Fwww.semanticweb.org%2Fontologies%2F2018%2F1%2FProstateCancer.owl%23Estramustine&apikey=YOUR_API_KEY"></iframe> For more help visit NCBO Widget Wiki |
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <link rel="stylesheet" type="text/css" href="/widgets/jquery.ncbo.tree.css"> <script src="/widgets/jquery.ncbo.tree-2.0.2.js"></script> <div id="widget_tree"></div> var widget_tree = $("#widget_tree").NCBOTree({ apikey: "YOUR_API_KEY", ontology: "PCAO" }); You can also view a detailed demonstration For more help visit NCBO Widget Wiki |