Prostate Cancer Ontology

Last uploaded: June 6, 2023
Preferred Name

Anti-androgens
Synonyms
Definitions

These oral compounds are classified according to their chemical structure as:|• steroidal, e.g. cyproterone acetate (CPA), megestrol acetate and medroxyprogesterone acetate;|• non-steroidal or pure, e.g. nilutamide, flutamide and bicalutamide.Both classes compete with androgens at the receptor level. This is the sole action of non-steroidal antiandrogens that leads to an unchanged or slightly elevated testosterone level. Conversely, steroidal|antiandrogens have progestational properties leading to a central inhibition by crossing the blood-brain barrier

ID

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Anti-androgens

ChineseLabel

抗雄激素

definition

These oral compounds are classified according to their chemical structure as:|• steroidal, e.g. cyproterone acetate (CPA), megestrol acetate and medroxyprogesterone acetate;|• non-steroidal or pure, e.g. nilutamide, flutamide and bicalutamide.Both classes compete with androgens at the receptor level. This is the sole action of non-steroidal antiandrogens that leads to an unchanged or slightly elevated testosterone level. Conversely, steroidal|antiandrogens have progestational properties leading to a central inhibition by crossing the blood-brain barrier

label

Anti-androgens

prefixIRI

ProstateCancer:Anti-androgens

prefLabel

Anti-androgens

subClassOf

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Hormonal_therapy

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