Preferred Name | Anti-androgens | |
Synonyms |
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Definitions |
These oral compounds are classified according to their chemical structure as:|• steroidal, e.g. cyproterone acetate (CPA), megestrol acetate and medroxyprogesterone acetate;|• non-steroidal or pure, e.g. nilutamide, flutamide and bicalutamide.Both classes compete with androgens at the receptor level. This is the sole action of non-steroidal antiandrogens that leads to an unchanged or slightly elevated testosterone level. Conversely, steroidal|antiandrogens have progestational properties leading to a central inhibition by crossing the blood-brain barrier |
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ID |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Anti-androgens |
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ChineseLabel |
抗雄激素 |
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definition |
These oral compounds are classified according to their chemical structure as:|• steroidal, e.g. cyproterone acetate (CPA), megestrol acetate and medroxyprogesterone acetate;|• non-steroidal or pure, e.g. nilutamide, flutamide and bicalutamide.Both classes compete with androgens at the receptor level. This is the sole action of non-steroidal antiandrogens that leads to an unchanged or slightly elevated testosterone level. Conversely, steroidal|antiandrogens have progestational properties leading to a central inhibition by crossing the blood-brain barrier |
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label |
Anti-androgens |
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prefixIRI |
ProstateCancer:Anti-androgens |
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prefLabel |
Anti-androgens |
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subClassOf |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Hormonal_therapy |
Delete | Mapping To | Ontology | Source |
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http://www.phoc.org.cn/pmo/class/PMO_00026178 | PMAPP-PMO | LOOM | |
http://purl.bioontology.org/ontology/RCD/x000T | RCD | LOOM | |
http://www.phoc.org.cn/pmo/class/PMO_00025834 | PMAPP-PMO | LOOM | |
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Antiandrogens | APAONTO | LOOM |