loading...| Preferred Name |
Autoimmune hepatitis |
|
| Synonyms |
AIH |
|
| Definitions |
A rare liver disease characterized by immune-mediated, acute or chronic liver inflammation, clinically presenting as cryptogenic hepatitis, with interface hepatitis on histological examination, elevated serum aminotransferase levels, and hypergammaglobulinemia / elevated immunoglobulin G, in the presence or absence of specific circulating autoantibodies. Patients may be asymptomatic, chronically ill, or present with acute liver failure. Concurrent autoimmune diseases are frequently observed. |
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| ID |
http://www.orpha.net/ORDO/Orphanet_2137 |
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| alternative_term |
AIH |
|
| definition |
A rare liver disease characterized by immune-mediated, acute or chronic liver inflammation, clinically presenting as cryptogenic hepatitis, with interface hepatitis on histological examination, elevated serum aminotransferase levels, and hypergammaglobulinemia / elevated immunoglobulin G, in the presence or absence of specific circulating autoantibodies. Patients may be asymptomatic, chronically ill, or present with acute liver failure. Concurrent autoimmune diseases are frequently observed. |
|
| definition_citation |
Orphanet |
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| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2137 |
|
| has_age_of_onset |
Adolescent Adult Childhood Elderly |
|
| has_inheritance |
Not applicable |
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| hasDbXref |
ICD-10:K75.4 UMLS:C4721555 ICD-11:DB96.0 MedDRA:10003827 |
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| label |
Autoimmune hepatitis |
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| notation |
ORPHA:2137 |
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_2137 |
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| prefLabel |
Autoimmune hepatitis |
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| present_in |
New Zealand AND has_point_prevalence_average_value : 24.5 AND has_point_prevalence_range : 1-5 / 10 000 Europe AND has_annual_incidence_average_value : 0.75 AND has_annual_incidence_range : 1-9 / 1 000 000 Norway AND has_point_prevalence_average_value : 16.9 AND has_point_prevalence_range : 1-5 / 10 000 Sweden AND has_annual_incidence_average_value : 0.85 AND has_annual_incidence_range : 1-9 / 1 000 000 Norway AND has_annual_incidence_average_value : 1.9 AND has_annual_incidence_range : 1-9 / 100 000 Spain AND has_point_prevalence_average_value : 11.6 AND has_point_prevalence_range : 1-5 / 10 000 Spain AND has_annual_incidence_average_value : 0.95 AND has_annual_incidence_range : 1-9 / 1 000 000 Denmark AND has_point_prevalence_average_value : 23.9 AND has_point_prevalence_range : 1-5 / 10 000 Denmark AND has_annual_incidence_average_value : 1.68 AND has_annual_incidence_range : 1-9 / 100 000 Singapore AND has_point_prevalence_average_value : 4.0 AND has_point_prevalence_range : 1-9 / 100 000 Worldwide AND has_point_prevalence_average_value : 23.5 AND has_point_prevalence_range : 1-5 / 10 000 Israel AND has_point_prevalence_average_value : 11.0 AND has_point_prevalence_range : 1-5 / 10 000 Specific population AND has_point_prevalence_average_value : 42.9 AND has_point_prevalence_range : 1-5 / 10 000 Israel AND has_annual_incidence_average_value : 0.67 AND has_annual_incidence_range : 1-9 / 1 000 000 Worldwide AND has_annual_incidence_average_value : 1.2 AND has_annual_incidence_range : 1-9 / 100 000 Sweden AND has_point_prevalence_average_value : 10.7 AND has_point_prevalence_range : 1-5 / 10 000 Europe AND has_point_prevalence_range : 1-5 / 10 000 |
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| treeView | ||
| subClassOf |