Preferred Name |
Nitric Oxide |
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Synonyms |
Nitrogen oxide (NO) |
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Definitions |
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCL (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C0028128 |
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altLabel |
Nitrogen oxide (NO) NO Nitric oxide vasodilators pulmonary nitric oxide Endogenous Nitrate Vasodilator Nitric oxide gas nitrogen protoxide Endothelium-Derived Relaxing Factor Oxyde azotique Nitrogen Monoxide Nitric Oxide, Endothelium-Derived Oxyde nitrique Monoxyde d'azote dérivé de l'endothélium EDRF endothelial cell derived relaxing factor Mononitrogen Monoxide |
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contraindicated_drug | ||
definition |
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCL (source : MSH) |
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hiddenLabel |
MonoxydeD'azote NitricOxide |
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induces | ||
prefixIRI |
OntoAD:C0028128 |
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prefLabel |
Monoxyde d'azote Nitric Oxide |
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subClassOf |
http://doe-generated-ontology.com/OntoAD#C0028167 http://doe-generated-ontology.com/OntoAD#C2143186 |